Vancomycin

What it is used for

Vancomycin hydrochloride capsules are indicated for the treatment of Clostridioides difficil e-associated diarrhea. Vancomycin hydrochloride capsules are also used for the treatment of enterocolitis caused by Staphylococcus aureus (including methicillin-resistant strains) in adult and pediatric patients less than 18 years of age.

Limitations of Use Parenteral administration of vancomycin is not effective for the above infections; therefore, vancomycin hydrochloride capsules must be given orally for these infections. Orally administered vancomycin hydrochloride capsules are not effective for other types of infections. To reduce the development of drug-resistant bacteria and maintain the effectiveness of vancomycin hydrochloride capsules and other antibacterial drugs, vancomycin hydrochloride capsules should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.

When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Side effects, and when to stop

The following clinically significant adverse reactions are described elsewhere in the labeling:

• Infusion Reactions
• Nephrotoxicity
• Ototoxicity
• Severe Dermatologic Reactions
• Clostridioides Difficile -Associated Diarrhea
• Hemorrhagic Occlusive Retinal Vasculitis
• Neutropenia
• Phlebitis and Other Administration Site Reactions

Who should not take it

TYZAVAN is contraindicated in patients with known hypersensitivity to vancomycin.

Storing it

Store at 15°C to 25°C (59°F to 77ºF), in original package. Use within 28 days of removal from aluminum overpouch.