Rasburicase

What it is used for

Elitek is indicated for the initial management of plasma uric acid levels in pediatric and adult patients with leukemia, lymphoma, and solid tumor malignancies who are receiving anticancer therapy expected to result in tumor lysis and subsequent elevation of plasma uric acid.

Side effects, and when to stop

The following clinically significant adverse reactions are discussed in greater detail in other sections of the prescribing information:

• Anaphylaxis
• Hemolysis
• Methemoglobinemia

Who should not take it

Elitek is contraindicated in patients with a history of anaphylaxis or severe hypersensitivity to rasburicase or in patients with development of hemolytic reactions or methemoglobinemia with rasburicase.

Elitek is contraindicated in individuals deficient in glucose-6-phosphate dehydrogenase (G6PD).

Storing it

Storage and Handling

The lyophilized drug product and the diluent for reconstitution should be stored at 2°C-8°C (36°F-46°F). Do not freeze. Protect from light.