Rasagiline

Rasagiline tablets are indicated for the treatment of Parkinson's disease (PD).

Prescribing label

Selected manufacturer label information, organised into consistent sections by Sofidex. This source is written for healthcare professionals; ask your pharmacist to explain instructions that are unclear. Read the full label at DailyMed ↗

Drug facts

Used for: Rasagiline tablets are indicated for the treatment of Parkinson's disease (PD).
Do not take if: Rasagiline tablet is contraindicated for use with meperidine, tramadol, methadone, propoxyphene, and MAO inhibitors (MAOIs), including other selective MAO-B inhibitors, because of risk of serotonin syndrome.
At least 14 days should elapse between discontinuation of rasagiline tablet and initiation of treatment with these medications.

Side effects, and when to stop

The following adverse reactions are described in more detail in the Warnings and Precautions section of the label:

Hypertension [ see Warnings and Precautions ]
Serotonin Syndrome [ see Warnings and Precautions ]
Falling Asleep During Activities of Daily Living and Somnolence [ see Warnings and Precautions ]
Hypotension / Orthostatic Hypotension [ see Warnings and Precautions ]
Dyskinesia [ see Warnings and Precautions ]
Hallucinations / Psychotic-Like Behavior [ see Warnings and Precautions ]
Impulse Control /Compulsive Behaviors [ see Warnings and Precautions ]
Withdrawal-Emergent Hyperpyrexia and Confusion [ see Warnings and Precautions ]

Who should not take it

Rasagiline tablet is contraindicated for use with meperidine, tramadol, methadone, propoxyphene, and MAO inhibitors (MAOIs), including other selective MAO-B inhibitors, because of risk of serotonin syndrome. At least 14 days should elapse between discontinuation of rasagiline tablet and initiation of treatment with these medications.

Rasagiline tablet is contraindicated for use with St. John’s wort and with cyclobenzaprine.

Rasagiline tablet is contraindicated for use with dextromethorphan because of risk of episode of psychosis or bizarre behavior.

Cite this page

NLM: sofidex [Internet]. Daloreum; c2026. Rasagiline; [reviewed 2026 Aug 3; cited 2026 Nov 10]. Available from: https://sofidex.com/patients/medicines/rasagiline
APA 7th: sofidex. (2026, August 3). Rasagiline. Daloreum. Retrieved November 10, 2026, from https://sofidex.com/patients/medicines/rasagiline
AMA 11th: Rasagiline. sofidex. Reviewed August 3, 2026. Accessed November 10, 2026. https://sofidex.com/patients/medicines/rasagiline

The cited date is today’s, because a citation records when you read the page. The reviewed date is when a clinician last checked it.