sofidexFor patientsAre you a clinician? Clinical site
Ask Sofi
Listen
Patient SupportEmergencies & Reporting
Log inSign up

Meds & supplements  ›  Pitolisant

Medicine

Pitolisant

WAKIX is indicated for the treatment of excessive daytime sleepiness (EDS) or cataplexy in patients 6 years of age and older with narcolepsy.

Prescribing label

Selected manufacturer label information, organised into consistent sections by Sofidex. This source is written for healthcare professionals; ask your pharmacist to explain instructions that are unclear. Read the full label at DailyMed ↗

Drug facts

Used for
WAKIX is indicated for the treatment of excessive daytime sleepiness (EDS) or cataplexy in patients 6 years of age and older with narcolepsy.
Do not take if
  • known hypersensitivity to pitolisant or any component of the formulation. Anaphylaxis has been reported in patients treated with WAKIX.
  • severe hepatic impairment. WAKIX is extensively metabolized by the liver and there is a significant increase in WAKIX exposure in patients with moderate hepatic impairment.

Side effects, and when to stop

The following adverse reactions are discussed in more detail in other sections of the labeling:

  • QT Interval Prolongation

Who should not take it

WAKIX is contraindicated in patients with:

  • known hypersensitivity to pitolisant or any component of the formulation. Anaphylaxis has been reported in patients treated with WAKIX.
  • severe hepatic impairment. WAKIX is extensively metabolized by the liver and there is a significant increase in WAKIX exposure in patients with moderate hepatic impairment.

Storing it

Store at 20° C to 25° C (68° F to 77° F); excursions permitted between 15° C to 30° C (59° F to 86° F).

Cite this page

NLM

sofidex [Internet]. Daloreum; c2026. Pitolisant; [reviewed 2026 Aug 3; cited 2026 Nov 10]. Available from: https://sofidex.com/patients/medicines/pitolisant

APA 7th

sofidex. (2026, August 3). Pitolisant. Daloreum. Retrieved November 10, 2026, from https://sofidex.com/patients/medicines/pitolisant

AMA 11th

Pitolisant. sofidex. Reviewed August 3, 2026. Accessed November 10, 2026. https://sofidex.com/patients/medicines/pitolisant

The cited date is today’s, because a citation records when you read the page. The reviewed date is when a clinician last checked it.