Cysteine

Side effects, and when to stop

The following serious adverse reactions are discussed in greater detail in other sections of the prescribing information:

• Pulmonary embolism due to pulmonary vascular precipitates
• Vein damage and thrombosis
• Increased BUN
• Acid-base imbalance
• Hepatobiliary disorders
• Aluminum toxicity

Adverse reactions with the use of cysteine hydrochloride injection were identified in clinical studies or postmarketing reports. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to estimate their frequency reliably or to establish a causal relationship to drug exposure.

• Metabolic acidosis
• Local infusion site reactions, including a warm sensation, erythema, phlebitis, and thrombosis at the infusion site
• Generalized flushing, fever, and nausea

Who should not take it

Cysteine hydrochloride injection, USP is contraindicated in:

• Patients with known hypersensitivity to one or more amino acids.
• Patients with inborn errors of amino acid metabolism due to risk of severe metabolic or neurologic complications.
• Patients with pulmonary edema or acidosis due to low cardiac output.