Updates ·
Health notices · Friday 14 August
3 notices from the agencies today, in plain words, each with the original linked.
Baxter recalls cefazolin in dextrose injection bags over particles
Food and Drug Administration (FDA)-SAFETY
If you were given cefazolin in dextrose injection, a nationwide voluntary recall is in place. Baxter says particulate matter was found in the solution.
The notice is about one product lot: Lot LD175708, with an expiration of 14-Feb-2027. It is described as a single-dose infusion bag in 100 ml.
Using a recalled product may carry an increased risk because particles were identified as cardboard. Follow the recall instructions from your care team or pharmacy.
Recall for certain dorzolamide and timolol eye drops bottles
FDA · Recall
If you use dorzolamide HCl and timolol maleate ophthalmic solution (eye drops), this affects you. The FDA reports complaints about defective bottles.
The issue is “broken cap spikes” and drops that are “undeliverable.” The product was distributed nationwide in the USA and was made by Micro Labs Limited (India).
If your bottle seems defective, you may not be able to use the drops as intended. You may need a replacement bottle if your pharmacy can supply one.
Thiopurines linked to intrahepatic cholestasis of pregnancy
Medicines and Healthcare products Regulatory Agency (MHRA) · Safety
If you take a thiopurine medicine in pregnancy (azathioprine, mercaptopurine or thioguanine), the MHRA reports a rare risk of intrahepatic cholestasis of pregnancy (ICP), a liver condition in pregnancy.
ICP can start earlier in pregnancy, and bile acid levels may not improve with ursodeoxycholic acid. Stopping or reducing the thiopurine may improve liver blood test results.
If you notice symptoms of ICP—intense itching without a rash, nausea, or loss of appetite—contact your doctor or midwife immediately. Do not stop your medicine unless they tell you to.
What to do
- Talk to your doctor or midwife immediately if you experience symptoms of cholestasis of pregnancy, including intense itching without a rash, nausea, and loss of appetite.
- Do not stop taking your medication unless advised to do so by your doctor or midwife.