Vonoprazan

VOQUEZNA is indicated: for healing of all grades of erosive esophagitis and relief of heartburn associated with erosive esophagitis in adults.

Prescribing label

Selected manufacturer label information, organised into consistent sections by Sofidex. This source is written for healthcare professionals; ask your pharmacist to explain instructions that are unclear. Read the full label at DailyMed ↗

Drug facts

Used for: for healing of all grades of erosive esophagitis and relief of heartburn associated with erosive esophagitis in adults.
to maintain healing of all grades of erosive esophagitis and relief of heartburn associated with erosive esophagitis in adults.
for the relief of heartburn associated with non-erosive gastroesophageal reflux disease in adults.
Do not take if: VOQUEZNA is contraindicated in patients with a known hypersensitivity to vonoprazan or any component of VOQUEZNA. Reactions have included anaphylactic shock.
VOQUEZNA is contraindicated with rilpivirine-containing products.
For information about contraindications of antibacterial agents (clarithromycin and amoxicillin) indicated in combination with VOQUEZNA, refer to the Contraindications section of the corresponding prescribing information.

What it is used for

VOQUEZNA is indicated:

for healing of all grades of erosive esophagitis and relief of heartburn associated with erosive esophagitis in adults.
to maintain healing of all grades of erosive esophagitis and relief of heartburn associated with erosive esophagitis in adults.
for the relief of heartburn associated with non-erosive gastroesophageal reflux disease in adults.
in combination with amoxicillin and clarithromycin for the treatment of Helicobacter pylori ( H. pylori ) infection in adults.
in combination with amoxicillin for the treatment of H. pylori infection in adults.

Side effects, and when to stop

The following serious adverse reactions are described elsewhere in labeling:

Acute Tubulointerstitial Nephritis
Clostridioides difficile -Associated Diarrhea
Bone Fracture
Severe Cutaneous Adverse Reactions
Vitamin B12 (Cobalamin) Deficiency
Hypomagnesemia and Mineral Metabolism
Fundic Gland Polyps

Who should not take it

VOQUEZNA is contraindicated in patients with a known hypersensitivity to vonoprazan or any component of VOQUEZNA. Reactions have included anaphylactic shock.
VOQUEZNA is contraindicated with rilpivirine-containing products.
For information about contraindications of antibacterial agents (clarithromycin and amoxicillin) indicated in combination with VOQUEZNA, refer to the Contraindications section of the corresponding prescribing information.

Other medicines and interactions

Table 9 and Table 10 include drugs with clinically important drug interactions and interaction with diagnostics when administered concomitantly with VOQUEZNA and instructions for preventing or managing them.

These recommendations are based on either drug interaction trials or predicted interactions due to the expected magnitude of interaction and potential for serious adverse reactions or loss of efficacy.

Consult the labeling of concomitantly used drugs to obtain further information about interactions with vonoprazan.

Storing it

Store between 20°C and 25°C (68°F and 77°F); excursions permitted between 15°C and 30°C (59°F and 86°F).

Cite this page

NLM: sofidex [Internet]. Daloreum; c2026. Vonoprazan; [reviewed 2026 Aug 3; cited 2026 Nov 10]. Available from: https://sofidex.com/patients/medicines/vonoprazan
APA 7th: sofidex. (2026, August 3). Vonoprazan. Daloreum. Retrieved November 10, 2026, from https://sofidex.com/patients/medicines/vonoprazan
AMA 11th: Vonoprazan. sofidex. Reviewed August 3, 2026. Accessed November 10, 2026. https://sofidex.com/patients/medicines/vonoprazan

The cited date is today’s, because a citation records when you read the page. The reviewed date is when a clinician last checked it.