sofidexFor patientsAre you a clinician? Clinical site
Ask Sofi
Listen
Patient SupportEmergencies & Reporting
Log inSign up

Meds & supplements  ›  Velpatasvir

Medicine · Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor

Velpatasvir

EPCLUSA™ is indicated for the treatment of adults and pediatric patients 6 years of age and older or weighing at least 17 kg with chronic hepatitis C virus (HCV) genotype 1, 2, 3, 4, 5

Prescribing label

Selected manufacturer label information, organised into consistent sections by Sofidex. This source is written for healthcare professionals; ask your pharmacist to explain instructions that are unclear. Read the full label at DailyMed ↗

Drug facts

Used for
  • without cirrhosis or with compensated cirrhosis
  • with decompensated cirrhosis for use in combination with ribavirin.
Do not take if
  • Sofosbuvir and velpatasvir and ribavirin combination regimen is contraindicated in patients for whom ribavirin is contraindicated.
  • Refer to the ribavirin prescribing information for a list of contraindications for ribavirin.

What it is used for

Sofosbuvir and velpatasvir is indicated for the treatment of adults and pediatric patients 3 years of age and older with chronic hepatitis C virus (HCV) genotype 1, 2, 3, 4, 5, or 6 infection:

  • without cirrhosis or with compensated cirrhosis
  • with decompensated cirrhosis for use in combination with ribavirin.

Side effects, and when to stop

The following serious adverse reactions are described below and elsewhere in labeling:

Who should not take it

Sofosbuvir and velpatasvir and ribavirin combination regimen is contraindicated in patients for whom ribavirin is contraindicated. Refer to the ribavirin prescribing information for a list of contraindications for ribavirin.

Storing it

Store below 30 °C (86 ºF).

Cite this page

NLM

sofidex [Internet]. Daloreum; c2026. Velpatasvir; [reviewed 2026 Aug 3; cited 2026 Nov 10]. Available from: https://sofidex.com/patients/medicines/velpatasvir

APA 7th

sofidex. (2026, August 3). Velpatasvir. Daloreum. Retrieved November 10, 2026, from https://sofidex.com/patients/medicines/velpatasvir

AMA 11th

Velpatasvir. sofidex. Reviewed August 3, 2026. Accessed November 10, 2026. https://sofidex.com/patients/medicines/velpatasvir

The cited date is today’s, because a citation records when you read the page. The reviewed date is when a clinician last checked it.