Vadadustat

VAFSEO is indicated for the treatment of anemia due to chronic kidney disease (CKD) in adults who have been receiving dialysis for at least three months.

Prescribing label

Selected manufacturer label information, organised into consistent sections by Sofidex. This source is written for healthcare professionals; ask your pharmacist to explain instructions that are unclear. Read the full label at DailyMed ↗

Drug facts

Used for: VAFSEO has not been shown to improve quality of life, fatigue, or patient well-being.
VAFSEO is not indicated for use:
As a substitute for red blood cell transfusions in patients who require immediate correction of anemia
Do not take if: with a known hypersensitivity to VAFSEO or any of its components.
with uncontrolled hypertension.

What it is used for

Limitations of Use

VAFSEO has not been shown to improve quality of life, fatigue, or patient well-being.
VAFSEO is not indicated for use:
- As a substitute for red blood cell transfusions in patients who require immediate correction of anemia
- In patients with anemia due to CKD not on dialysis.

Side effects, and when to stop

The following clinically significant adverse reactions are discussed elsewhere in the labeling:

Increased risk of death, myocardial infarction, stroke, venous thromboembolism, and thrombosis of vascular access
Hepatotoxicity
Hypertension
Seizures
Gastrointestinal erosion
Serious adverse reactions in patients with anemia due to chronic kidney disease and not on dialysis

Who should not take it

VAFSEO is contraindicated in patients:

with a known hypersensitivity to VAFSEO or any of its components.
with uncontrolled hypertension.

Storing it

Storage and Handling

Store at 20°C to 25°C (68°F to 77°F); excursions permitted between 15°C to 30°C (59°F to 86°F). Keep out of reach of children.

Cite this page

NLM: sofidex [Internet]. Daloreum; c2026. Vadadustat; [reviewed 2026 Aug 3; cited 2026 Nov 10]. Available from: https://sofidex.com/patients/medicines/vadadustat
APA 7th: sofidex. (2026, August 3). Vadadustat. Daloreum. Retrieved November 10, 2026, from https://sofidex.com/patients/medicines/vadadustat
AMA 11th: Vadadustat. sofidex. Reviewed August 3, 2026. Accessed November 10, 2026. https://sofidex.com/patients/medicines/vadadustat

The cited date is today’s, because a citation records when you read the page. The reviewed date is when a clinician last checked it.