Meds & supplements › Thiosulfate
Medicine
Thiosulfate
Sodium Thiosulfate Injection is indicated for sequential use with sodium nitrite for the treatment of acute cyanide poisoning that is judged to be serious or life-threatening.
Selected manufacturer label information, organised into consistent sections by Sofidex. This source is written for healthcare professionals; ask your pharmacist to explain instructions that are unclear. Read the full label at DailyMed ↗
Drug facts
- Used for
- Sodium Thiosulfate Injection is indicated for sequential use with sodium nitrite for the treatment of acute cyanide poisoning that is judged to be serious or life-threatening.
- Do not take if
- PEDMARK is contraindicated in patients with history of a severe hypersensitivity to sodium thiosulfate or any of its components.
What it is used for
PEDMARK is indicated to reduce the risk of ototoxicity associated with cisplatin in pediatric patients 1 month of age and older with localized, non-metastatic solid tumors.
Limitations of Use
The safety and efficacy of PEDMARK have not been established when administered following cisplatin infusions longer than 6 hours. PEDMARK may not reduce the risk of ototoxicity when administered following longer cisplatin infusions, because irreversible ototoxicity may have already occurred.
Side effects, and when to stop
The following clinically significant adverse reactions are described elsewhere in the labeling:
- Hypersensitivity
- Hypernatremia and Hypokalemia
- Nausea and Vomiting
Who should not take it
PEDMARK is contraindicated in patients with history of a severe hypersensitivity to sodium thiosulfate or any of its components.
Storing it
Store at 20°C to 25°C (68°F to 77°F); excursions are permitted between 15°C and 30°C (59°F to 86°F).
Cite this page
- NLM
sofidex [Internet]. Daloreum; c2026. Thiosulfate; [reviewed 2026 Aug 3; cited 2026 Nov 10]. Available from: https://sofidex.com/patients/medicines/thiosulfate
- APA 7th
sofidex. (2026, August 3). Thiosulfate. Daloreum. Retrieved November 10, 2026, from https://sofidex.com/patients/medicines/thiosulfate
- AMA 11th
Thiosulfate. sofidex. Reviewed August 3, 2026. Accessed November 10, 2026. https://sofidex.com/patients/medicines/thiosulfate
The cited date is today’s, because a citation records when you read the page. The reviewed date is when a clinician last checked it.