Tenecteplase

TNKase ® is indicated to reduce the risk of death associated with acute ST elevation myocardial infarction (STEMI).

Prescribing label

Selected manufacturer label information, organised into consistent sections by Sofidex. This source is written for healthcare professionals; ask your pharmacist to explain instructions that are unclear. Read the full label at DailyMed ↗

Drug facts

Used for: TNKase ® is indicated to reduce the risk of death associated with acute ST elevation myocardial infarction (STEMI).

What it is used for

TNKase ® is indicated to reduce the risk of death associated with acute ST elevation myocardial infarction (STEMI). TNKase is a tissue plasminogen activator, indicated to reduce the risk of death associated with acute ST elevation myocardial infarction (STEMI).

Side effects, and when to stop

The following clinically significant adverse reactions are discussed in other sections of the label:

Bleeding
Hypersensitivity
Thromboembolism
Cholesterol Embolization
Arrhythmias
Increased Risk of Heart Failure and Recurrent Ischemia when used with Planned Percutaneous Coronary Intervention (PCI) in STEMI

Storing it

Store lyophilized TNKase at room temperature up to 30°C (86°F) or refrigerated at 2°C to 8°C (36°F to 46°F). Do not use beyond the expiration date stamped on the vial.

For storage information for reconstituted TNKase, see Dosage and Administration.

Cite this page

NLM: sofidex [Internet]. Daloreum; c2026. Tenecteplase; [reviewed 2026 Aug 3; cited 2026 Nov 10]. Available from: https://sofidex.com/patients/medicines/tenecteplase
APA 7th: sofidex. (2026, August 3). Tenecteplase. Daloreum. Retrieved November 10, 2026, from https://sofidex.com/patients/medicines/tenecteplase
AMA 11th: Tenecteplase. sofidex. Reviewed August 3, 2026. Accessed November 10, 2026. https://sofidex.com/patients/medicines/tenecteplase

The cited date is today’s, because a citation records when you read the page. The reviewed date is when a clinician last checked it.