Sotatercept

What it is used for

WINREVAIR™ is indicated for the treatment of adults with pulmonary arterial hypertension (PAH, Group 1 pulmonary hypertension) to improve exercise capacity and World Health Organization (WHO) functional class (FC), and reduce the risk of clinical worsening events including hospitalization for PAH, lung transplantation and death.

Side effects, and when to stop

The following clinically significant adverse reactions are described elsewhere in the labeling:

• Erythrocytosis
• Severe Thrombocytopenia
• Serious Bleeding
• Embryo-Fetal Toxicity
• Impaired Fertility

Who should not take it

None.

Storing it

Store vials refrigerated at 2°C to 8°C (36°F to 46°F) in original carton to protect from light. Do not freeze.

The kit should remain in the refrigerator until ready for use. The unused kit can be out of the refrigerator for (up to 25°C/77°F) up to 24 hours. For additional information on temperature excursions, call Merck Sharp & Dohme LLC at 1-800-672-6372.