Meds & supplements › Oliceridine
Medicine
Oliceridine
OLINVYK is indicated in adults for the management of acute pain severe enough to require an intravenous opioid analgesic and for whom alternative treatments are inadequate.
Selected manufacturer label information, organised into consistent sections by Sofidex. This source is written for healthcare professionals; ask your pharmacist to explain instructions that are unclear. Read the full label at DailyMed ↗
Drug facts
- Used for
- The cumulative total daily dose should not exceed 27 mg, as total daily doses greater than 27 mg may increase the risk for QTc interval prolongation.
- OLINVYK is an opioid agonist indicated in adults for the management of acute pain severe enough to require an intravenous opioid analgesic and for whom alternative treatments are inadequate.
- Do not take if
- Significant respiratory depression
- Acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment
- Known or suspected gastrointestinal obstruction, including paralytic ileus
- Known hypersensitivity to oliceridine (e.g., anaphylaxis)
What it is used for
Limitations of Use
Because of the risks of addiction, abuse, misuse, overdose, and death, which can occur at any dosage or duration, and persist over the course of therapy, reserve opioid analgesics, including OLINVYK, for use in patients for whom alternative treatment options are ineffective, not management of pain.
The cumulative total daily dose should not exceed 27 mg, as total daily doses greater than 27 mg may increase the risk for QTc interval prolongation.
Side effects, and when to stop
The following adverse reactions are described, or described in greater detail, in other sections:
- Addiction, Abuse, and Misuse
- Life-threatening Respiratory Depression
- Interactions with Benzodiazepines or Other CNS Depressants
- Neonatal Opioid Withdrawal Syndrome
- Opioid-Induced Hyperalgesia and Allodynia
- Adrenal Insufficiency
- Severe Hypotension
- Gastrointestinal Adverse Reactions
- Seizures
- Withdrawal
Who should not take it
OLINVYK is contraindicated in patients with:
- Significant respiratory depression
- Acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment
- Known or suspected gastrointestinal obstruction, including paralytic ileus
- Known hypersensitivity to oliceridine (e.g., anaphylaxis)
Other medicines and interactions
Table 6 includes clinically significant drug interactions with OLINVYK.
Cite this page
- NLM
sofidex [Internet]. Daloreum; c2026. Oliceridine; [reviewed 2026 Aug 3; cited 2026 Nov 10]. Available from: https://sofidex.com/patients/medicines/oliceridine
- APA 7th
sofidex. (2026, August 3). Oliceridine. Daloreum. Retrieved November 10, 2026, from https://sofidex.com/patients/medicines/oliceridine
- AMA 11th
Oliceridine. sofidex. Reviewed August 3, 2026. Accessed November 10, 2026. https://sofidex.com/patients/medicines/oliceridine
The cited date is today’s, because a citation records when you read the page. The reviewed date is when a clinician last checked it.