Marstacimab

What it is used for

HYMPAVZI is indicated for routine prophylaxis to prevent or reduce the frequency of bleeding episodes in adults and pediatric patients 6 years of age and older with:

• hemophilia A (congenital factor VIII deficiency) with or without factor VIII inhibitors, or
• hemophilia B (congenital factor IX deficiency) with or without factor IX inhibitors.

Side effects, and when to stop

The following clinically significant adverse reactions are described elsewhere in the labeling:

• Thromboembolic Events
• Hypersensitivity

Who should not take it

None.

Other medicines and interactions

Partial Thromboplastin Time (aPTT) and Prothrombin Time (PT) No clinically significant differences in standard measures of coagulation including activated partial thromboplastin time (aPTT) and prothrombin time (PT) were observed following marstacimab‑hncq therapy.

Storing it

• Store refrigerated at 36°F to 46°F (2°C to 8°C) in the original carton to protect from light.
• If needed, HYMPAVZI may be stored one time at room temperature [up to 86°F (30°C)] in its original carton to protect from light for up to 7 days. Once stored at room temperature, do not return to the refrigerator and discard after 7 days.
• Do not freeze.
• Do not shake.