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Meds & supplements  ›  Lonafarnib

Medicine · Farnesyltransferase Inhibitor

Lonafarnib

ZOKINVY is indicated in patients 12 months of age and older with a body surface area (BSA) of 0.39 m 2 and above: To reduce the risk of mortality in Hutchinson-Gilford Progeria Syndrome (HGPS) For the treatment of processing-deficient…

Prescribing label

Selected manufacturer label information, organised into consistent sections by Sofidex. This source is written for healthcare professionals; ask your pharmacist to explain instructions that are unclear. Read the full label at DailyMed ↗

Drug facts

Used for
  • To reduce the risk of mortality in Hutchinson-Gilford Progeria Syndrome (HGPS)
  • For the treatment of processing-deficient Progeroid Laminopathies with either:
  • Heterozygous LMNA mutation with progerin-like protein accumulation
Do not take if

What it is used for

ZOKINVY is indicated in patients 12 months of age and older with a body surface area (BSA) of 0.39 m 2 and above:

  • To reduce the risk of mortality in Hutchinson-Gilford Progeria Syndrome (HGPS)
  • For the treatment of processing-deficient Progeroid Laminopathies with either:
    • Heterozygous LMNA mutation with progerin-like protein accumulation
    • Homozygous or compound heterozygous ZMPSTE24 mutations

Who should not take it

ZOKINVY is contraindicated in patients taking:

  • Strong CYP3A inhibitors
  • Strong or moderate CYP3A inducers
  • Midazolam
  • Lovastatin, simvastatin, or atorvastatin

Cite this page

NLM

sofidex [Internet]. Daloreum; c2026. Lonafarnib; [reviewed 2026 Aug 3; cited 2026 Nov 10]. Available from: https://sofidex.com/patients/medicines/lonafarnib

APA 7th

sofidex. (2026, August 3). Lonafarnib. Daloreum. Retrieved November 10, 2026, from https://sofidex.com/patients/medicines/lonafarnib

AMA 11th

Lonafarnib. sofidex. Reviewed August 3, 2026. Accessed November 10, 2026. https://sofidex.com/patients/medicines/lonafarnib

The cited date is today’s, because a citation records when you read the page. The reviewed date is when a clinician last checked it.