Liraglutide

What it is used for

Liraglutide injection is indicated: as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients aged 10 years and older with type 2 diabetes mellitus Limitations of Use: Liraglutide injection contains liraglutide. Coadministration with other liraglutide-containing products is not recommended.

Liraglutide injection is a glucagon-like peptide-1 (GLP-1) receptor agonist indicated: as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients aged 10 years and older with type 2 diabetes mellitus. Limitations of Use: Coadministration with other liraglutide-containing products is not recommended.

The most important thing to know

Liraglutide injection may cause serious side effects, including: Possible thyroid tumors, including cancer. Tell your healthcare provider if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In studies with rats and mice, liraglutide injection and medicines that work like liraglutide injection caused thyroid tumors, including thyroid cancer.

It is not known if liraglutide injection will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people. Do not use liraglutide injection if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC), or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

What is liraglutide injection? Liraglutide injection is an injectable prescription medicine used: along with diet and exercise to improve blood sugar (glucose) in adults and children who are 10 years of age and older with type 2 diabetes mellitus. Liraglutide injection is not recommended for people who take liraglutide or other medicines called glucagon-like peptide-1 (GLP-1) receptor agonists.

It is not known if liraglutide injection is safe and effective to lower blood sugar (glucose) in children under 10 years of age. Who should not use liraglutide injection? Do not use liraglutide injection if: you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

you have had a serious allergic reaction to liraglutide or any of the ingredients in liraglutide injection. See the end of this Medication Guide for a complete list of ingredients in liraglutide injection. See "

Side effects, and when to stop

" for symptoms of a serious allergic reaction.

Who should not take it

Do not take 2 doses of liraglutide injection at the same time Liraglutide injection may be taken with or without food. Do not mix insulin and liraglutide injection together in the same injection. You may give an injection of liraglutide injection and insulin in the same body area (such as your stomach area), but not right next to each other.

Change (rotate) your injection site with each injection. Do not use the same site for each injection. Do not share your liraglutide injection pen with other people, even if the needle has been changed. You may give other people a serious infection or get a serious infection from them. If you take too much liraglutide injection, call your healthcare provider or the Poison Help line at 1-800-222-1222 or go to the nearest hospital emergency room right away.

The liraglutide injection pen you are using should be thrown away 30 days after you start using it. What are the possible side effects of liraglutide injection? Liraglutide injection may cause serious side effects, including: inflammation of your pancreas (pancreatitis). Stop using liraglutide injection and call your healthcare provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without vomiting.

You may feel the pain from your abdomen to your back. low blood sugar (hypoglycemia). Your risk for getting low blood sugar may be higher if you use liraglutide injection with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin. In children who are 10 years of age and older, the risk for low blood sugar may be higher with liraglutide injection regardless of use with another medicine that can also lower blood sugar.

Signs and symptoms of low blood sugar may include: ο dizziness or light-headedness ο sweating ο confusion or drowsiness ο headache ο blurred vision ο slurred speech ο shakiness ο fast heartbeat ο anxiety, irritability, or mood changes ο hunger ο weakness ο feeling jittery dehydration leading to kidney problems. Diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration) which may cause kidney problems.

It is important for you to drink fluids to help reduce your chance of dehydration. Tell your healthcare provider right away if you have nausea, vomiting, or diarrhea that does not go away. s evere stomach problems. Stomach problems, sometimes severe, have been reported in people who use liraglutide injection. Tell your healthcare provider if you have stomach problems that are severe or will not go away.

serious allergic reactions. Stop using liraglutide injection and get medical help right away, if you have any symptoms of a serious allergic reaction including: ο swelling of your face, lips, tongue or throat ο problems breathing or swallowing ο severe rash or itching ο fainting or feeling dizzy ο very rapid heartbeat gallbladder problems.

Gallbladder problems have happened in some people who take liraglutide injection. Tell your healthcare provider right away if you get symptoms of gallbladder problems which may include: ο pain in your upper stomach (abdomen) ο fever ο yellowing of skin or eyes (jaundice) ο clay-colored stools food or liquid getting into the lungs during surgery or other procedures that use anesthesia or deep sleepiness (deep sedation).

Liraglutide injection may increase the chance of food getting into your lungs during surgery or other procedures. Tell all your healthcare providers that you are taking liraglutide injection before you are scheduled to have surgery or other procedures. The most common side effects of liraglutide injection may include nausea, diarrhea, vomiting, decreased appetite, indigestion and constipation.

Talk to your healthcare provider about any side effects that bothers you or does not go away. These are not all the possible side effects of liraglutide injection. Call your doctor for med

What to say before you start

Before using liraglutide injection, tell your healthcare provider if you have any other medical conditions, including if you: have or have had problems with your pancreas. have severe problems with your stomach, such as slowed emptying of your stomach (gastroparesis) or problems with digesting food. are scheduled to have surgery or other procedures that use anesthesia or deep sleepiness (deep sedation).

are pregnant or plan to become pregnant. It is not known if liraglutide injection will harm your unborn baby. Tell your healthcare provider if you become pregnant while using liraglutide injection. are breastfeeding or plan to breastfeed. It is not known if liraglutide passes into your breast milk. You should talk with your healthcare provider about the best way to feed your baby while using liraglutide injection.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Liraglutide injection may affect the way some medicines work and some medicines may affect the way liraglutide injection works. Before using liraglutide injection, talk to your healthcare provider about low blood sugar and how to manage it.

Tell your healthcare provider if you are taking other medicines to treat diabetes, including insulin or sulfonylureas. Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine. How should I use liraglutide injection? Read the Instructions for Use that comes with liraglutide injection.

Use liraglutide injection exactly as your healthcare provider tells you to. Your healthcare provider should show you how to use liraglutide injection before you use it for the first time. Inject your dose of liraglutide injection under the skin (subcutaneously) of your stomach (abdomen), thigh, or upper arm. Do not inject liraglutide injection into a muscle (intramuscularly) or vein (intravenously).

Use liraglutide injection 1 time each day, at any time of the day. If you miss a dose of liraglutide injection, take the missed dose at the next scheduled dose.