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Meds & supplements  ›  Ledipasvir

Medicine · Hepatitis C Virus NS5A Inhibitor

Ledipasvir

Ledipasvir and sofosbuvir is indicated for the treatment of adults and pediatric patients 3 years of age and older with chronic hepatitis C virus (HCV): genotype 1, 4, 5

Prescribing label

Selected manufacturer label information, organised into consistent sections by Sofidex. This source is written for healthcare professionals; ask your pharmacist to explain instructions that are unclear. Read the full label at DailyMed ↗

Drug facts

Used for
  • genotype 1, 4, 5, or 6 infection without cirrhosis or with compensated cirrhosis
  • genotype 1 infection with decompensated cirrhosis, for use in combination with ribavirin
  • genotype 1 or 4 infection who are liver transplant recipients without cirrhosis or with compensated cirrhosis, for use in combination with ribavirin
Do not take if
  • If ledipasvir and sofosbuvir is administered with ribavirin, the contraindications to ribavirin also apply to this combination regimen.
  • Refer to the ribavirin prescribing information for a list of contraindications for ribavirin.

What it is used for

Ledipasvir and sofosbuvir is indicated for the treatment of adults and pediatric patients 3 years of age and older with chronic hepatitis C virus (HCV):

  • genotype 1, 4, 5, or 6 infection without cirrhosis or with compensated cirrhosis
  • genotype 1 infection with decompensated cirrhosis, for use in combination with ribavirin
  • genotype 1 or 4 infection who are liver transplant recipients without cirrhosis or with compensated cirrhosis, for use in combination with ribavirin

Side effects, and when to stop

The following serious adverse reactions are described below and elsewhere in labeling:

Who should not take it

If ledipasvir and sofosbuvir is administered with ribavirin, the contraindications to ribavirin also apply to this combination regimen. Refer to the ribavirin prescribing information for a list of contraindications for ribavirin.

Storing it

Store at room temperature below 30 °C (86 °F).

Cite this page

NLM

sofidex [Internet]. Daloreum; c2026. Ledipasvir; [reviewed 2026 Aug 3; cited 2026 Nov 10]. Available from: https://sofidex.com/patients/medicines/ledipasvir

APA 7th

sofidex. (2026, August 3). Ledipasvir. Daloreum. Retrieved November 10, 2026, from https://sofidex.com/patients/medicines/ledipasvir

AMA 11th

Ledipasvir. sofidex. Reviewed August 3, 2026. Accessed November 10, 2026. https://sofidex.com/patients/medicines/ledipasvir

The cited date is today’s, because a citation records when you read the page. The reviewed date is when a clinician last checked it.