Insulin glargine

What it is used for

Insulin Glargine, U-300 is indicated to improve glycemic control in adults and pediatric patients 6 years of age and older with diabetes mellitus.

Side effects, and when to stop

The following adverse reactions are discussed elsewhere:

• Hyperglycemia or Hypoglycemia with Changes in Insulin Regimen.
• Hypoglycemia
• Hypoglycemia Due to Medication Errors
• Hypersensitivity Reactions
• Hypokalemia

Who should not take it

Insulin Glargine, U-300 is contraindicated:

• During episodes of hypoglycemia.
• In patients with hypersensitivity to insulin glargine or any excipients in Insulin Glargine, U-300.

Other medicines and interactions

Table 3 includes clinically significant drug interactions with Insulin Glargine, U-300.

Storing it

Dispense in the original sealed carton with the enclosed Instructions for Use.

Insulin Glargine, U-300 SoloStar or Insulin Glargine, U-300 Max SoloStar prefilled pen should not be stored in the freezer and should not be allowed to freeze. Discard Insulin Glargine, U-300 prefilled pen if it has been frozen. Protect Insulin Glargine, U-300 SoloStar/ Insulin Glargine, U-300 Max SoloStar from direct heat and light.

Storage conditions are summarized in the following table: