Gatifloxacin

What it is used for

ZYMAXID ® is indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of the following organisms:

• Aerobic gram-positive bacteria: Staphylococcus aureus Staphylococcus epidermidis Streptococcus mitis group * Streptococcus oralis * Streptococcus pneumoniae

• Aerobic gram-negative bacteria: Haemophilus influenzae

*Efficacy for these organisms were studied in fewer than 10 infections.

Side effects, and when to stop

The following serious adverse reactions are described elsewhere in the labeling:

• Hypersensitivity [ see Contraindications ( 4 ) and Warnings and Precautions ( 5.1 ) ]
• Growth of Resistant Organisms With Prolonged Use [ see Warnings and Precautions ( 5.2 ) ]
• Corneal Endothelial Cell Injury [ see Warnings and Precautions ( 5.3 ) ]

Who should not take it

ZYMAXID ® is contraindicated in patients with a history of hypersensitivity to gatifloxacin, to other quinolones, or to any of the components in this medication.

2 dosage and administration

• Day 1: Instill one drop every two hours in the affected eye(s) while awake, up to 8 times.
• Day 2 through Day 7: Instill one drop two to four times daily in the affected eye(s) while awake.