Droxidopa

What it is used for

Droxidopa capsules are indicated for the treatment of orthostatic dizziness, lightheadedness, or the “feeling that you are about to black out” in adult patients with symptomatic neurogenic orthostatic hypotension (nOH) caused by primary autonomic failure (Parkinson's disease [PD], multiple system atrophy, and pure autonomic failure), dopamine beta-hydroxylase deficiency, and non-diabetic autonomic neuropathy. Effectiveness beyond 2 weeks of treatment has not been established. The continued effectiveness of droxidopa capsules should be assessed periodically.

Side effects, and when to stop

The following adverse reactions with droxidopa are included in more detail in the Warnings and Precautions section of the label:

• Supine Hypertension [ see Warnings and Precautions ( 5.1 )]
• Hyperpyrexia and Confusion [ see Warnings and Precautions ( 5.2 )]
• May exacerbate existing ischemic heart disease, arrhythmias, and congestive heart failure [ see Warnings and Precautions ( 5.3 )]

Who should not take it

Droxidopa capsules are contraindicated in patients who have a history of hypersensitivity to the drug or its ingredients.