Doxorubicin

Doxorubicin Hydrochloride Injection is an anthracycline topoisomerase inhibitor

Prescribing label

Selected manufacturer label information, organised into consistent sections by Sofidex. This source is written for healthcare professionals; ask your pharmacist to explain instructions that are unclear. Read the full label at DailyMed ↗

Drug facts

Used for: as a component of multi-agent adjuvant chemotherapy
for treatment of women with axillary lymph node involvement following resection of primary breast cancer
for the treatment of: acute lymphoblastic leukemia, acute myeloblastic leukemia, Hodgkin lymphoma, Non-Hodgkin lymphoma, metastatic breast cancer, metastatic Wilms' tumor, metastatic neuroblastoma, metastatic soft tissue sarcoma, metastatic bone sarcomas, metastatic ovarian carcinoma, metastatic transitional cell bladder carcinoma, metastatic thyroid carcinoma, metastatic gastric carcinoma, metastatic bronchogenic carcinoma 1.1 Adjuvant Breast Cancer Doxorubicin Hydrochloride Injection is indicated as a component of multi-agent adjuvant chemotherapy
Do not take if: Severe myocardial insufficiency
Recent (occurring within the past 4 to 6 weeks) myocardial infarction
Severe persistent drug-induced myelosuppression
Severe hepatic impairment (defined as Child Pugh Class C or serum bilirubin level greater than 5 mg/dL)

What it is used for

Doxorubicin Hydrochloride Injection is an anthracycline topoisomerase inhibitor indicated: as a component of multi-agent adjuvant chemotherapy for treatment of women with axillary lymph node involvement following resection of primary breast cancer for the treatment of: acute lymphoblastic leukemia, acute myeloblastic leukemia, Hodgkin lymphoma, Non-Hodgkin lymphoma, metastatic breast cancer, metastatic Wilms' tumor, metastatic neuroblastoma, metastatic soft tissue sarcoma, metastatic bone sarcomas, metastatic ovarian carcinoma, metastatic transitional cell bladder carcinoma, metastatic thyroid carcinoma, metastatic gastric carcinoma, metastatic bronchogenic carcinoma 1.1 Adjuvant Breast Cancer Doxorubicin Hydrochloride Injection is indicated as a component of multi-agent adjuvant chemotherapy for treatment of women with axillary lymph node involvement following resection of primary breast cancer.

Other Cancers Doxorubicin Hydrochloride Injection is indicated for the treatment of acute lymphoblastic leukemia acute myeloblastic leukemia Hodgkin lymphoma non-Hodgkin lymphoma (NHL) metastatic breast cancer metastatic Wilms' tumor metastatic neuroblastoma metastatic soft tissue sarcoma metastatic bone sarcoma metastatic ovarian carcinoma metastatic transitional cell bladder carcinoma metastatic thyroid carcinoma metastatic gastric carcinoma metastatic bronchogenic carcinoma

Side effects, and when to stop

The following clinically significant adverse reactions are described elsewhere in the labeling.

Cardiomyopathy and Arrhythmias
Secondary Malignancies
Extravasation and Tissue Necrosis
Severe Myelosuppression
Tumor Lysis Syndrome
Radiation Sensitization and Radiation Recall

Who should not take it

Doxorubicin hydrochloride for injection is contraindicated in patients with:

Severe myocardial insufficiency
Recent (occurring within the past 4 to 6 weeks) myocardial infarction
Severe persistent drug-induced myelosuppression
Severe hepatic impairment (defined as Child Pugh Class C or serum bilirubin level greater than 5 mg/dL)
Severe hypersensitivity reaction to doxorubicin hydrochloride, including anaphylaxis

Cite this page

NLM: sofidex [Internet]. Daloreum; c2026. Doxorubicin; [reviewed 2026 Aug 2; cited 2026 Nov 10]. Available from: https://sofidex.com/patients/medicines/doxorubicin
APA 7th: sofidex. (2026, August 2). Doxorubicin. Daloreum. Retrieved November 10, 2026, from https://sofidex.com/patients/medicines/doxorubicin
AMA 11th: Doxorubicin. sofidex. Reviewed August 2, 2026. Accessed November 10, 2026. https://sofidex.com/patients/medicines/doxorubicin

The cited date is today’s, because a citation records when you read the page. The reviewed date is when a clinician last checked it.