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Meds & supplements  ›  Cenobamate

Medicine

Cenobamate

XCOPRI is indicated for the treatment of partial-onset seizures in adult patients.

Prescribing label

Selected manufacturer label information, organised into consistent sections by Sofidex. This source is written for healthcare professionals; ask your pharmacist to explain instructions that are unclear. Read the full label at DailyMed ↗

Drug facts

Used for
XCOPRI is indicated for the treatment of partial-onset seizures in adult patients.
Do not take if
  • Hypersensitivity to cenobamate or any of the inactive ingredients in XCOPRI
  • Familial Short QT syndrome

Side effects, and when to stop

The following serious adverse reactions are described in more detail in the Warnings and Precautions section of the labeling:

  • Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)/Multiorgan Hypersensitivity
  • QT Shortening
  • Suicidal Behavior and Ideation
  • Liver Injury
  • Neurological Adverse Reactions
  • Withdrawal of Antiepileptic Drugs

Who should not take it

XCOPRI is contraindicated in patients with:

  • Hypersensitivity to cenobamate or any of the inactive ingredients in XCOPRI
  • Familial Short QT syndrome

Storing it

Store XCOPRI tablets at 20°C to 25°C (68°F to 77°F) with excursions permitted to 15°C to 30°C (59°F to 86°F) (See USP Controlled Room Temperature).

16.1 How Supplied

XCOPRI tablets are supplied in the following configurations:

Bottles; 30 count

Titration Blister Packs; 14-Day

Titration Blister Packs; 28-Day

Maintenance Blister Packs; 28-Day

Cite this page

NLM

sofidex [Internet]. Daloreum; c2026. Cenobamate; [reviewed 2026 Aug 2; cited 2026 Nov 10]. Available from: https://sofidex.com/patients/medicines/cenobamate

APA 7th

sofidex. (2026, August 2). Cenobamate. Daloreum. Retrieved November 10, 2026, from https://sofidex.com/patients/medicines/cenobamate

AMA 11th

Cenobamate. sofidex. Reviewed August 2, 2026. Accessed November 10, 2026. https://sofidex.com/patients/medicines/cenobamate

The cited date is today’s, because a citation records when you read the page. The reviewed date is when a clinician last checked it.