Bivalirudin

What it is used for

Bivalirudin for injection is indicated for use as an anticoagulant for use in patients undergoing percutaneous coronary intervention (PCI) including patients with heparin-induced thrombocytopenia and heparin-induced thrombocytopenia and thrombosis syndrome.

Who should not take it

Bivalirudin for injection is contraindicated in patients with:

• Active major bleeding;
• Hypersensitivity (e.g., anaphylaxis) to bivalirudin for injection or its components.

Other medicines and interactions

In clinical trials in patients undergoing PCI/ percutaneous transluminal coronary angioplasty(PTCA), co-administration of bivalirudin for injection with heparin, warfarin, thrombolytics, orGPIs was associated with increased risks of major bleeding events compared to patients notreceiving these concomitant medications.