Meds & supplements › Anacaulase
Medicine
Anacaulase
NEXOBRID is indicated for eschar removal in adults and pediatric patients with deep partial thickness (DPT) and/or full thickness (FT) thermal burns.
Selected manufacturer label information, organised into consistent sections by Sofidex. This source is written for healthcare professionals; ask your pharmacist to explain instructions that are unclear. Read the full label at DailyMed ↗
Drug facts
- Used for
- Chemical or electrical burns
- Burns on the face, perineum, or genitalia
- Burns on the feet of patients with diabetes mellitus or on the feet of patients with occlusive vascular disease
- Do not take if
- Known hypersensitivity to anacaulase-bcdb, bromelain, pineapples, or to any of the other components.
- Known hypersensitivity to papayas or papain because of the risk of cross-sensitivity.
What it is used for
Limitations of Use
The safety and effectiveness of NEXOBRID have not been established for treatment of:
- Chemical or electrical burns
- Burns on the face, perineum, or genitalia
- Burns on the feet of patients with diabetes mellitus or on the feet of patients with occlusive vascular disease
- Circumferential burns
- Burns in patients with significant cardiopulmonary disease, including inhalation injury
NEXOBRID is not recommended for:
- Wounds contaminated with radioactive and other hazardous substances to avoid unforeseeable reactions with the product and an increased risk of spreading the noxious substance.
- Treatment of burn wounds where medical devices (e.g., implants, pacemakers, shunts) or vital structures (e.g., large vessels) could become exposed during eschar removal.
Side effects, and when to stop
The following clinically significant adverse reactions are described elsewhere in the labeling:
- Hypersensitivity Reactions
Who should not take it
NEXOBRID is contraindicated in patients with:
- Known hypersensitivity to anacaulase-bcdb, bromelain, pineapples, or to any of the other components.
- Known hypersensitivity to papayas or papain because of the risk of cross-sensitivity.
Cite this page
- NLM
sofidex [Internet]. Daloreum; c2026. Anacaulase; [reviewed 2026 Aug 2; cited 2026 Nov 10]. Available from: https://sofidex.com/patients/medicines/anacaulase
- APA 7th
sofidex. (2026, August 2). Anacaulase. Daloreum. Retrieved November 10, 2026, from https://sofidex.com/patients/medicines/anacaulase
- AMA 11th
Anacaulase. sofidex. Reviewed August 2, 2026. Accessed November 10, 2026. https://sofidex.com/patients/medicines/anacaulase
The cited date is today’s, because a citation records when you read the page. The reviewed date is when a clinician last checked it.