Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
1
Is any of this happening now?
Call 911
Seek emergency medical help for:
Sudden loss or major change in vision
New confusion, fainting, severe dizziness, or difficulty speaking
New weakness or numbness affecting one side of the body
A severe or rapidly worsening headache
Chest pain or severe difficulty breathing
Heavy bleeding that does not stop
These symptoms can have causes other than Waldenstrom macroglobulinemia, but they require immediate assessment.
Other emergency signs, for anyone
Someone who is struggling to breathe, gasping, choking, or cannot get words out
Someone who has chest pain, tightness or pressure lasting more than a few minutes
Someone who has sudden weakness or drooping on one side of the face or body, slurred speech, or sudden confusion
Someone who is unconscious, or cannot be woken
Someone who is bleeding heavily and it will not stop with firm pressure
Someone who has had a seizure that will not stop, or does not wake up afterwards
Someone who has lips or skin that look pale, blue, grey or blotchy
Someone who you believe has taken an overdose or swallowed something poisonous
2
Is any of this happening?
Be seen today
Contact your care team promptly for worsening shortness of breath, increasing weakness, new bleeding, rapidly increasing swelling, fever during treatment, or symptoms of an infection.
Follow any specific instructions you have been given for fever or low blood counts.
3
Does any of this apply?
Book an appointment
Arrange a routine appointment if you develop persistent fatigue, new numbness or burning in your hands or feet, increasing bruising, repeated infections, swollen lymph nodes, or unexplained weight loss.
If you already have the condition, report new symptoms rather than waiting for the next planned blood test.
Every sign above is quoted from the sofidex article on Waldenstrom macroglobulinemia. If you are not sure, err upward — it is always reasonable to be checked.