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Warning-sign checks

Transplant rejection: when to get help

Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.

  1. 1

    Is any of this happening now?

    Call 911

    Seek emergency help for severe difficulty breathing, blue or grey lips, crushing or persistent chest pain, fainting, new confusion, heavy bleeding, or sudden severe abdominal pain.

    Also use emergency services for any rapidly worsening symptom that may represent organ failure.

    Other emergency signs, for anyone
    • Someone who is struggling to breathe, gasping, choking, or cannot get words out
    • Someone who has chest pain, tightness or pressure lasting more than a few minutes
    • Someone who has sudden weakness or drooping on one side of the face or body, slurred speech, or sudden confusion
    • Someone who is unconscious, or cannot be woken
    • Someone who is bleeding heavily and it will not stop with firm pressure
    • Someone who has had a seizure that will not stop, or does not wake up afterwards
    • Someone who has lips or skin that look pale, blue, grey or blotchy
    • Someone who you believe has taken an overdose or swallowed something poisonous
  2. 2

    Is any of this happening?

    Be seen today

    Contact your transplant team promptly if you develop a new symptom that could reflect rejection, infection, or a medication problem.

    This includes:

    • Fever or chills
    • New pain or tenderness over the transplant
    • Vomiting or diarrhea that prevents you keeping medicines down
    • Reduced urine, new swelling, or rapid fluid-related weight gain
    • Yellow skin or eyes
    • New cough, breathlessness, or lower home lung readings
    • Rising blood glucose after a pancreas transplant
    • An abnormal home measurement your team told you to report
    • A missed anti-rejection dose or uncertainty about how to take it

    These concerns usually need same-day advice rather than waiting for a routine appointment.

    Do not wait for several symptoms to appear.

  3. 3

    Does any of this apply?

    Book an appointment

    Keep attending routine follow-up when you feel well.

    Monitoring is designed to find silent rejection before it causes major symptoms.

Every sign above is quoted from the sofidex article on Transplant rejection. If you are not sure, err upward — it is always reasonable to be checked.