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Warning-sign checks

Thrombotic thrombocytopenic purpura: when to get help

Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.

  1. 1

    Is any of this happening now?

    Call 911

    A suspected first episode or relapse of TTP needs emergency assessment.

    Call emergency services for:

    • New confusion, trouble speaking, facial drooping, or weakness
    • A seizure, collapse, or loss of consciousness
    • Chest pain, severe breathlessness, or fainting
    • Sudden severe headache, especially with neurological symptoms
    • Heavy or uncontrolled bleeding
    Other emergency signs, for anyone
    • Someone who is struggling to breathe, gasping, choking, or cannot get words out
    • Someone who has chest pain, tightness or pressure lasting more than a few minutes
    • Someone who has sudden weakness or drooping on one side of the face or body, slurred speech, or sudden confusion
    • Someone who is unconscious, or cannot be woken
    • Someone who is bleeding heavily and it will not stop with firm pressure
    • Someone who has had a seizure that will not stop, or does not wake up afterwards
    • Someone who has lips or skin that look pale, blue, grey or blotchy
    • Someone who you believe has taken an overdose or swallowed something poisonous
  2. 2

    Is any of this happening?

    Be seen today

    Seek urgent same-day assessment for new unexplained bruising, petechiae, dark urine, marked tiredness, yellow skin or eyes, or a persistent headache.

    Do not wait for a routine appointment if these symptoms could represent a relapse.

    Contact the treatment team sooner if symptoms change between appointments.

  3. 3

    Does any of this apply?

    Book an appointment

    Routine follow-up is for monitoring while you feel well, discussing ongoing fatigue or concentration problems, reviewing medicines, and planning pregnancy, travel, surgery, or dental procedures.

The article also says

If you have previously had TTP, follow your specialist relapse plan.

Every sign above is quoted from the sofidex article on Thrombotic thrombocytopenic purpura. If you are not sure, err upward — it is always reasonable to be checked.