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Warning-sign checks

Syndrome of inappropriate antidiuretic hormone secretion: when to get help

Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.

  1. 1

    Is any of this happening now?

    Call 911

    Seek emergency medical help for:

    • A seizure
    • Loss of consciousness or difficulty waking
    • Sudden severe confusion
    • Serious breathing difficulty
    Other emergency signs, for anyone
    • Someone who is struggling to breathe, gasping, choking, or cannot get words out
    • Someone who has chest pain, tightness or pressure lasting more than a few minutes
    • Someone who has sudden weakness or drooping on one side of the face or body, slurred speech, or sudden confusion
    • Someone who is unconscious, or cannot be woken
    • Someone who is bleeding heavily and it will not stop with firm pressure
    • Someone who has had a seizure that will not stop, or does not wake up afterwards
    • Someone who has lips or skin that look pale, blue, grey or blotchy
    • Someone who you believe has taken an overdose or swallowed something poisonous
  2. 2

    Is any of this happening?

    Be seen today

    These symptoms may indicate severe hyponatremia or another urgent condition.

    Seek prompt medical advice for new confusion, repeated vomiting, a severe or worsening headache, marked drowsiness, major weakness, or rapidly worsening balance.

    This is especially important if you have known SIADH or recently started a medicine associated with low sodium.

  3. 3

    Does any of this apply?

    Book an appointment

    Arrange routine follow-up if thirst, cramps, tiredness, nausea, concentration problems, or unsteadiness continue.

    Also seek advice if a fluid restriction is difficult to follow, if you become unwell with vomiting or diarrhea, or if your medicines change.

    Do not adjust a prescribed fluid plan based only on symptoms.

Every sign above is quoted from the sofidex article on Syndrome of inappropriate antidiuretic hormone secretion. If you are not sure, err upward — it is always reasonable to be checked.