Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
Seek emergency care for a hand that suddenly becomes cold, pale, blue, very painful, numb, or weak, especially after an injury.
Sudden arm weakness with facial drooping or difficulty speaking also needs emergency care.
These are circulation or nervous-system warning signs, not features of a single palmar crease.
Seek same-day medical advice for new palm or hand swelling, redness, warmth, worsening pain, or loss of movement.
These symptoms are unlikely to be caused by the crease, but they may need treatment for an injury, infection, or another hand problem.
If the crease has been present from birth and there are no other concerns, it can usually be mentioned at a routine health appointment.
No special visit is generally needed for the crease alone.
Book a routine appointment if a baby or child also has:
These findings do not confirm a diagnosis.
They simply give a clinician a reason to assess the child more fully.
Every sign above is quoted from the sofidex article on Single palmar crease. If you are not sure, err upward — it is always reasonable to be checked.