Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
1
Is any of this happening now?
Call 911
Call emergency services for:
Chest pain, severe breathlessness, or collapse
Fainting with injury or failure to recover promptly
Sudden facial drooping, arm weakness, or speech difficulty
Severe weakness that appears suddenly rather than gradually
Other emergency signs, for anyone
Someone who is struggling to breathe, gasping, choking, or cannot get words out
Someone who has chest pain, tightness or pressure lasting more than a few minutes
Someone who has sudden weakness or drooping on one side of the face or body, slurred speech, or sudden confusion
Someone who is unconscious, or cannot be woken
Someone who is bleeding heavily and it will not stop with firm pressure
Someone who has had a seizure that will not stop, or does not wake up afterwards
Someone who has lips or skin that look pale, blue, grey or blotchy
Someone who you believe has taken an overdose or swallowed something poisonous
2
Is any of this happening?
Be seen today
Seek urgent medical advice for rapidly worsening swelling, new repeated fainting, a sustained racing or irregular heartbeat, or a major reduction in urine output.
These signs can have causes other than amyloidosis, but they require prompt assessment.
3
Does any of this apply?
Book an appointment
Arrange a routine medical appointment if you develop persistent numbness, burning pain, unexplained weakness, dizziness when standing, ongoing bowel changes, ankle swelling, or declining exercise tolerance.
These symptoms have several possible causes and need assessment rather than self-diagnosis.
You should also seek routine advice if a biological relative is diagnosed with hereditary ATTR amyloidosis or a disease-causing TTR gene change.
Genetic testing is best arranged with counselling so that you understand what the result can and cannot show.
Every sign above is quoted from the sofidex article on Ohio type amyloidosis. If you are not sure, err upward — it is always reasonable to be checked.