Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
1
Is any of this happening now?
Call 911
Seek emergency care for:
Severe trouble breathing, especially with swelling
Chest pain, fainting or confusion
Very little or no urine with worsening illness
A seizure, sudden weakness or difficulty speaking
Signs of a severe allergic reaction, such as facial swelling and breathing difficulty
Other emergency signs, for anyone
Someone who is struggling to breathe, gasping, choking, or cannot get words out
Someone who has chest pain, tightness or pressure lasting more than a few minutes
Someone who has sudden weakness or drooping on one side of the face or body, slurred speech, or sudden confusion
Someone who is unconscious, or cannot be woken
Someone who is bleeding heavily and it will not stop with firm pressure
Someone who has had a seizure that will not stop, or does not wake up afterwards
Someone who has lips or skin that look pale, blue, grey or blotchy
Someone who you believe has taken an overdose or swallowed something poisonous
2
Is any of this happening?
Be seen today
Arrange a routine or prompt medical review if you notice new foamy urine, ankle or facial swelling, visible blood in your urine, higher blood pressure or unexplained weight gain.
Also seek advice if known lupus symptoms are returning or medication side effects are difficult to manage.
Contact your care team promptly if you are passing much less urine than usual, swelling is increasing quickly, or you develop fever or infection symptoms while taking immune-suppressing medicine.
These symptoms can have several causes and do not always mean lupus nephritis is worsening, but they need urgent assessment.
And for anyone, someone who:
has a wound that is hot, spreading red, or leaking pus
Every sign above is quoted from the sofidex article on Lupus nephritis. If you are not sure, err upward — it is always reasonable to be checked.