Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
1
Is any of this happening now?
Call 911
Seek emergency care for:
Chest pain or pressure
Severe or sudden shortness of breath
Fainting with slow recovery, injury, or palpitations
New facial drooping, arm weakness, or difficulty speaking
Inability to keep fluids down with signs of dehydration
Other emergency signs, for anyone
Someone who is struggling to breathe, gasping, choking, or cannot get words out
Someone who has chest pain, tightness or pressure lasting more than a few minutes
Someone who has sudden weakness or drooping on one side of the face or body, slurred speech, or sudden confusion
Someone who is unconscious, or cannot be woken
Someone who is bleeding heavily and it will not stop with firm pressure
Someone who has had a seizure that will not stop, or does not wake up afterwards
Someone who has lips or skin that look pale, blue, grey or blotchy
Someone who you believe has taken an overdose or swallowed something poisonous
2
Is any of this happening?
Be seen today
Contact your amyloidosis or cardiology team promptly if you have repeated fainting, rapidly increasing swelling, a new irregular heartbeat, or a clear decline in walking or hand function.
These symptoms can have several causes and require urgent assessment rather than waiting for a routine appointment.
3
Does any of this apply?
Book an appointment
Arrange routine medical review if you develop new or increasing numbness, weakness, balance problems, bowel changes, dizziness on standing, ankle swelling, breathlessness during usual activities, or unexplained weight loss.
These symptoms do not prove that amyloidosis is worsening, but they deserve assessment.
Every sign above is quoted from the sofidex article on Isoleucine 33 amyloidosis. If you are not sure, err upward — it is always reasonable to be checked.