Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
Call emergency services for:
These symptoms can indicate serious bleeding, infection, or severe anemia.
Contact your hematology team urgently if you develop a temperature of 38°C or 100.4°F or higher, unless your team has given you a different threshold.
Also seek urgent advice for chills, sudden illness, a new cough, painful urination, or other possible signs of infection.
Get urgent medical help for new or increasing bruising, persistent nosebleeds, bleeding gums, blood in urine, black bowel movements, or menstrual bleeding that is much heavier than usual.
Do not wait for the next planned visit if symptoms are clearly worsening.
For routine follow-up, tell your medical team about steadily increasing fatigue, breathlessness during normal activity, more frequent infections, medication side effects, or difficulty managing appointments and daily activities.
Every sign above is quoted from the sofidex article on Idiopathic aplastic anemia. If you are not sure, err upward — it is always reasonable to be checked.