Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
1
Is any of this happening now?
Call 911
Seek emergency help for:
Severe difficulty breathing
Chest pain that does not settle
Fainting or collapse
A very fast or irregular heartbeat with weakness or breathlessness
Sudden facial drooping, arm weakness, or trouble speaking
These symptoms do not necessarily mean amyloidosis has worsened, but they can signal a serious heart, circulation, or neurological problem.
Other emergency signs, for anyone
Someone who is struggling to breathe, gasping, choking, or cannot get words out
Someone who has chest pain, tightness or pressure lasting more than a few minutes
Someone who has sudden weakness or drooping on one side of the face or body, slurred speech, or sudden confusion
Someone who is unconscious, or cannot be woken
Someone who is bleeding heavily and it will not stop with firm pressure
Someone who has had a seizure that will not stop, or does not wake up afterwards
Someone who has lips or skin that look pale, blue, grey or blotchy
Someone who you believe has taken an overdose or swallowed something poisonous
2
Is any of this happening?
Be seen today
If you already have amyloidosis, contact your care team promptly for a clear increase in swelling, rapidly worsening breathlessness, new palpitations, reduced urine output, repeated dizziness, or difficulty keeping down food and fluids.
3
Does any of this apply?
Book an appointment
Arrange a routine medical appointment if you develop persistent unexplained swelling, foamy urine, breathlessness, numbness, weight loss, easy bruising, or dizziness when standing.
These symptoms have many possible causes, but they deserve assessment if they continue.
These changes may need earlier review rather than waiting for a scheduled appointment.
Every sign above is quoted from the sofidex article on Idiopathic amyloidosis. If you are not sure, err upward — it is always reasonable to be checked.