Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
1
Is any of this happening now?
Call 911
These symptoms need assessment but are not always emergencies.
Seek emergency help for possible signs of a blood clot or stroke, including:
Sudden weakness, numbness, facial drooping, or difficulty speaking
Sudden loss of vision or a severe new neurological symptom
New chest pain, coughing up blood, or unexplained shortness of breath
Painful swelling, warmth, or redness in one leg
Collapse, severe confusion, or a seizure lasting longer than usual
Other emergency signs, for anyone
Someone who is struggling to breathe, gasping, choking, or cannot get words out
Someone who has chest pain, tightness or pressure lasting more than a few minutes
Someone who has sudden weakness or drooping on one side of the face or body, slurred speech, or sudden confusion
Someone who is unconscious, or cannot be woken
Someone who is bleeding heavily and it will not stop with firm pressure
Someone who has had a seizure that will not stop, or does not wake up afterwards
Someone who has lips or skin that look pale, blue, grey or blotchy
Someone who you believe has taken an overdose or swallowed something poisonous
2
Is any of this happening?
Be seen today
Contact your metabolic team promptly if you cannot take your usual treatment, have repeated vomiting or diarrhoea, become dehydrated, or expect to have surgery.
Planning is also important before pregnancy and during long journeys or periods of reduced movement.
These symptoms can have several causes, but they require urgent assessment.
3
Does any of this apply?
Book an appointment
Arrange routine medical advice if you develop new blurred vision, rapidly changing eyesight, bone pain, repeated fractures, worsening balance, seizures, or changes in learning, behaviour, or mood.
Every sign above is quoted from the sofidex article on Homocystinuria. If you are not sure, err upward — it is always reasonable to be checked.