Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
1
Is any of this happening now?
Call 911
Call emergency services for severe trouble breathing, fainting, confusion, uncontrolled bleeding, signs of severe dehydration, or a rapidly worsening reaction affecting the skin or several organs.
Other emergency signs, for anyone
Someone who is struggling to breathe, gasping, choking, or cannot get words out
Someone who has chest pain, tightness or pressure lasting more than a few minutes
Someone who has sudden weakness or drooping on one side of the face or body, slurred speech, or sudden confusion
Someone who is unconscious, or cannot be woken
Someone who is bleeding heavily and it will not stop with firm pressure
Someone who has had a seizure that will not stop, or does not wake up afterwards
Someone who has lips or skin that look pale, blue, grey or blotchy
Someone who you believe has taken an overdose or swallowed something poisonous
2
Is any of this happening?
Be seen today
Contact your transplant team promptly about any new symptom that could represent GVHD or infection.
Early assessment is especially important for a new rash, ongoing vomiting or diarrhoea, yellow skin or eyes, worsening mouth pain, painful eyes, or a new cough.
Seek same-day medical advice for:
Rapidly spreading rash, blistering, or skin peeling
Frequent watery diarrhoea, blood in stool, or inability to keep fluids down
New jaundice or very dark urine
Fever at or above the threshold given by your transplant team
New shortness of breath, wheezing, or a clear fall in exercise tolerance
Severe eye pain, light sensitivity, or a sudden vision change
Do not wait for a routine appointment if symptoms are new or getting worse.
3
Does any of this apply?
Book an appointment
Stable symptoms, medicine side effects, rehabilitation needs, and routine monitoring can usually be discussed at planned follow-up.
Every sign above is quoted from the sofidex article on GVHD. If you are not sure, err upward — it is always reasonable to be checked.