Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
Seek emergency care for severe difficulty breathing, fainting, chest pain, sudden weakness or numbness on one side, trouble speaking, a new severe loss of balance, or another possible sign of stroke.
Contact a clinician promptly for a clear increase in swelling, rapid weight gain, worsening shortness of breath, repeated dizziness, new palpitations, persistent vomiting or diarrhea, or a foot wound that is not healing.
These symptoms require urgent assessment and should not wait for a routine amyloidosis appointment.
Routine follow-up usually includes review of breathing, swelling, weight, heart rhythm symptoms, blood pressure, walking, sensation, digestion, and daily function.
Depending on organ involvement, clinicians may repeat blood tests, electrocardiograms, heart imaging, rhythm monitoring, or neurologic assessments.
Follow-up also helps the care team decide whether symptoms reflect amyloidosis, treatment effects, or another condition.
Relatives who carry the variant but do not have symptoms may be offered planned surveillance.
The timing and tests should be based on age, family history, the specific variant, and specialist advice.
Predictive genetic testing is best arranged through genetic counseling, particularly when the person being tested is healthy.
The article also says
People taking disease-modifying therapy need monitoring appropriate to the medicine.
Every sign above is quoted from the sofidex article on Appalachian type amyloidosis. If you are not sure, err upward — it is always reasonable to be checked.