sofidexFor patientsAre you a clinician? Clinical site

Warning-sign checks

Aplastic anemia: when to get help

Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.

  1. 1

    Is any of this happening now?

    Call 911

    Severe breathing difficulty, chest pain, fainting, confusion, neurologic symptoms, or uncontrolled bleeding require emergency care.

    Other emergency signs, for anyone
    • Someone who is struggling to breathe, gasping, choking, or cannot get words out
    • Someone who has chest pain, tightness or pressure lasting more than a few minutes
    • Someone who has sudden weakness or drooping on one side of the face or body, slurred speech, or sudden confusion
    • Someone who is unconscious, or cannot be woken
    • Someone who is bleeding heavily and it will not stop with firm pressure
    • Someone who has had a seizure that will not stop, or does not wake up afterwards
    • Someone who has lips or skin that look pale, blue, grey or blotchy
    • Someone who you believe has taken an overdose or swallowed something poisonous
  2. 2

    Is any of this happening?

    Be seen today

    Between visits, contact the treatment team promptly for a fever, new signs of infection, worsening shortness of breath, or unusual bleeding.

  3. 3

    Does any of this apply?

    Book an appointment

    Follow-up is usually more frequent during diagnosis and active treatment.

    It may become less frequent after blood counts stabilize, but long-term hematology care is still important.

    Routine follow-up is the right time to discuss fatigue, menstrual bleeding, bruising, medication effects, emotional health, fertility, work or school needs, and infection precautions.

    Patients who have received many transfusions may also need monitoring for iron overload.

The article also says

Visits may include a complete blood count, reticulocyte count, medicine review, and tests of kidney or liver function.

Doctors may periodically check for a PNH cell population or signs of abnormal marrow cell growth.

A repeat bone marrow biopsy may be recommended if counts worsen, new cell abnormalities appear, or the treatment response is unclear.

Every sign above is quoted from the sofidex article on Aplastic anemia. If you are not sure, err upward — it is always reasonable to be checked.