Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
1
Is any of this happening now?
Call 911
Do not stop an important prescription medicine on your own unless emergency clinicians advise you to do so; contact the prescriber promptly for guidance.
Tongue or throat swelling, breathing difficulty, faintness, or suspected anaphylaxis requires emergency services rather than routine follow-up.
Other emergency signs, for anyone
Someone who is struggling to breathe, gasping, choking, or cannot get words out
Someone who has chest pain, tightness or pressure lasting more than a few minutes
Someone who has sudden weakness or drooping on one side of the face or body, slurred speech, or sudden confusion
Someone who is unconscious, or cannot be woken
Someone who is bleeding heavily and it will not stop with firm pressure
Someone who has had a seizure that will not stop, or does not wake up afterwards
Someone who has lips or skin that look pale, blue, grey or blotchy
Someone who you believe has taken an overdose or swallowed something poisonous
2
Is any of this happening?
Be seen today
Seek urgent medical advice for significant abdominal pain, repeated vomiting, dehydration, or rapidly worsening swelling, even when breathing is normal.
And for anyone, someone who:
is getting rapidly more short of breath, or has gained several pounds in a few days with swelling
3
Does any of this apply?
Book an appointment
Routine follow-up is appropriate after a first unexplained episode, repeated swelling, or any episode linked to a medicine.
Bring photographs, a symptom timeline, and a complete medicine list.
A follow-up plan may cover:
How to recognize an attack and when to use rescue treatment
Which symptoms require emergency care
Whether medicines or procedures may trigger attacks
How and where emergency medicines should be stored
Planning for travel, school, work, dental treatment, or surgery
Whether family members should be tested
The article also says
Referral to an allergist or immunologist may be helpful when attacks recur, occur without hives, involve the abdomen, are linked to an ACE inhibitor, or raise concern for hereditary or acquired angioedema.
Relatives of a person with confirmed HAE may be offered evaluation.
Every sign above is quoted from the sofidex article on Angioedema. If you are not sure, err upward — it is always reasonable to be checked.