Go through these in order and stop at the first one that applies. If you are reading this for someone else, answer for them.
Severe pain, fainting, confusion, breathing difficulty, or a rigid or swollen abdomen requires emergency evaluation.
Seek urgent care for new bloody diarrhea, worsening abdominal pain, repeated vomiting, dehydration, or fever.
Follow-up depends on the form of amebiasis and how well symptoms respond.
Keep scheduled appointments and tell the clinician if diarrhea, blood in the stool, fever, or abdominal pain continues after treatment.
Seek routine medical follow-up for mild symptoms that persist, medication side effects, or questions about testing household or sexual contacts.
The article also says
A clinician may order repeat stool testing to check whether the infection has cleared.
The need for testing can depend on the original test, ongoing symptoms, risk of transmission, and local public health rules.
Do not use leftover medicine or repeat treatment without medical advice because persistent symptoms may have another cause.
After treatment for a liver abscess, symptoms and blood test results usually guide recovery.
Imaging changes can take longer to disappear than pain or fever, so an abnormal scan does not necessarily mean that active infection remains.
The treating clinician will decide whether repeat imaging is useful.
To reduce reinfection and protect others, wash hands carefully, follow food and water precautions, and avoid sexual practices that may expose a partner to stool until treatment is complete and a clinician has advised that transmission risk has passed.
Every sign above is quoted from the sofidex article on Amebiasis. If you are not sure, err upward — it is always reasonable to be checked.